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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                    FORM 11-K

             FOR ANNUAL REPORTS OF EMPLOYEE STOCK PURCHASE, SAVINGS
               AND SIMILAR PLANS PURSUANT TO SECTION 15(d) OF THE
                        SECURITIES EXCHANGE ACT OF 1934

                         ------------------------------

               [X] ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                   For the Fiscal Year Ended December 31, 2004

                                       OR

             [ ] TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE
                        SECURITIES EXCHANGE ACT OF 1934

                         Commission File Number 1-3215

                         ------------------------------

                                JOHNSON & JOHNSON
                             RETIREMENT SAVINGS PLAN

                            (Full title of the Plan)

                                JOHNSON & JOHNSON
                           ONE JOHNSON & JOHNSON PLAZA
                         NEW BRUNSWICK, NEW JERSEY 08933

           (Name of issuer of the securities held pursuant to the Plan
               and the address of its principal executive office)

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                              REQUIRED INFORMATION

Item 4. Financial Statements and Exhibits

      Financial statements prepared in accordance with the financial reporting
requirements of ERISA filed herewith are listed below in lieu of the
requirements of Items 1 to 3.


      Report of Independent Registered Public Accounting Firm

      Financial Statements:

            Statements of Net Assets Available for Benefits

            Statement of Changes in Net Assets Available for Benefits

      Notes to Financial Statements

Schedules required by Section 2520.103.10 of the Department of Labor's Rules and
Regulations for Reporting and Disclosure under ERISA have been omitted because
they are not required or are not applicable.

Exhibits:

    23.     Consent of PricewaterhouseCoopers LLP, dated June 24, 2005



                                   SIGNATURES

The Plan. Pursuant to the requirements of the Securities Exchange Act of 1934,
the trustees (or other persons who administer the employee benefit plan) have
duly caused this annual report to be signed on its behalf by the undersigned
hereunto duly authorized.

                                       JOHNSON & JOHNSON RETIREMENT SAVINGS PLAN

                                                 By: /s/ R. J. Darretta
                                                     --------------------------
                                                     R. J. Darretta
                                                     Chairman, Pension Committee

June 27, 2005



                    JOHNSON & JOHNSON RETIREMENT SAVINGS PLAN

                               ------------------

                              FINANCIAL STATEMENTS

                           DECEMBER 31, 2004 AND 2003



JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

INDEX TO FINANCIAL STATEMENTS
DECEMBER 31, 2004 AND 2003
--------------------------------------------------------------------------------



                                                                   PAGE(S)
                                                                
Report of Independent Registered Public Accounting Firm               1

Financial Statements:

   Statements of Net Assets Available for Benefits                    2

   Statement of Changes in Net Assets Available for Benefits          3

Notes to Financial Statements                                       4 - 9


Schedules required by Section 2520.103.10 of the Department of Labor's Rules and
Regulations for Reporting and Disclosure under ERISA have been omitted because
they are not required or are not applicable.



            REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Participants, the Pension Committee and the
Compensation & Benefits Committee of the
Johnson & Johnson Retirement Savings Plan:

In our opinion, the accompanying statements of net assets available for benefits
and the related statement of changes in net assets available for benefits
present fairly, in all material respects, the net assets available for benefits
of the Johnson & Johnson Retirement Savings Plan (the "Plan") as of December 31,
2004 and 2003, and the changes in net assets available for benefits for the year
ended December 31, 2004 in conformity with accounting principles generally
accepted in the United States of America. These financial statements are the
responsibility of the Plan's management. Our responsibility is to express an
opinion on these financial statements based on our audits. We conducted our
audits of these statements in accordance with the standards of the Public
Company Accounting Oversight Board (United States). Those standards require that
we plan and perform the audit to obtain reasonable assurance about whether the
financial statements are free of material misstatement. An audit includes
examining, on a test basis, evidence supporting the amounts and disclosures in
the financial statements, assessing the accounting principles used and
significant estimates made by management, and evaluating the overall financial
statement presentation. We believe that our audits provide a reasonable basis
for our opinion.

/s/ PricewaterhouseCoopers LLP
--------------------------------

Florham Park, New Jersey
June 24, 2005


                                      -1-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

STATEMENTS OF NET ASSETS AVAILABLE FOR BENEFITS
DECEMBER 31, 2004 AND 2003
--------------------------------------------------------------------------------



                                                          2004           2003
                                                               
ASSETS
    Interest in Johnson & Johnson Pension
      and Savings Plans Master Trust, at fair value   $135,917,302   $106,429,400
                                                      ------------   ------------

        Total investments                              135,917,302    106,429,400

    Receivables
      Employee contributions                               320,808        282,555
      Employer contributions                               117,904        104,265
                                                      ------------   ------------

        Total receivables                                  438,712        386,820
                                                      ------------   ------------

        Total assets                                   136,356,014    106,816,220
                                                      ============   ============

LIABILITIES
    Accrued expenses                                        51,711         52,680
                                                      ------------   ------------

        Total liabilitites                                  51,711         52,680
                                                      ============   ============

           Net assets available for benefits          $136,304,303   $106,763,540
                                                      ============   ============


   The accompanying notes are an integral part of these financial statements.

                                       -2-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

STATEMENT OF CHANGES IN NET ASSETS AVAILABLE FOR BENEFITS
DECEMBER 31, 2004
--------------------------------------------------------------------------------



                                                          
ADDITIONS TO NET ASSETS ATTRIBUTED TO
    Investment income
      Plan's interest in the Johnson & Johnson Pension and
        Savings Plans Master Trust net appreciation          $ 21,529,110
      Interest                                                    255,921
      Dividends                                                 2,013,275

    Contributions
      Employee contributions                                   11,674,563
      Employer contributions                                    4,409,837
                                                             ------------

        Total additions                                        39,882,706
                                                             ------------

DEDUCTIONS FROM NET ASSETS ATTRIBUTED TO
    Benefits paid to participants                              10,025,320
    Administrative expenses                                       316,623
                                                             ------------

        Total deductions                                       10,341,943
                                                             ------------

           Net increase                                        29,540,763

NET ASSETS AVAILABLE FOR BENEFITS
    Beginning of year                                         106,763,540
                                                             ------------

    End of year                                              $136,304,303
                                                             ------------


   The accompanying notes are an integral part of these financial statements.

                                       -3-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

1.    DESCRIPTION OF PLAN

      GENERAL

      The Johnson & Johnson Retirement Savings Plan (the "Plan") is a defined
      contribution plan which was established on March 1, 1990 for eligible
      employees of certain participating subsidiaries of Johnson & Johnson
      ("J&J" or the "Company") located in Puerto Rico which have adopted the
      Plan. The Plan was designed to provide eligible employees with an
      opportunity to strengthen their financial security at retirement by
      providing an incentive to save and invest regularly. The funding of the
      Plan is made through employee and Company contributions. Beginning January
      1, 2003, assets of the Plan are maintained in the Johnson & Johnson
      Pension and Savings Plans Master Trust (the "Trust"). The Plan's interest
      in the Johnson & Johnson Pension and Savings Plans Master Trust is
      allocated to the Plan based upon the total of each participant's share in
      the Trust.

      As of January 1, 2003, State Street Bank and Trust Company ("State
      Street") serves as agent and custodian of the Plan for purposes of
      investment of the assets of the Trust, maintained by Banco Popular de
      Puerto Rico. As such, State Street performs certain services for the Plan,
      including the execution of certain participant directed investments, which
      are commingled for investment purposes only with assets of other
      tax-qualified plans maintained by Johnson & Johnson. Prior to January 1,
      2003, the assets of the Plan were maintained and transactions therein were
      executed by Banco Popular de Puerto Rico.

      This brief description of the Plan is provided for general information
      purposes only. Participants should refer to the Plan document for complete
      information.

      CONTRIBUTIONS

      In general, salaried and hourly employees of participating Johnson &
      Johnson companies who are Puerto Rico residents can contribute to the Plan
      immediately.

      Contributions are made to the Plan by participants through payroll
      deductions and by the Company on behalf of participants. Participating
      employees may contribute a minimum of 3% up to a maximum of 10% pre-tax
      and/or a minimum of 1% up to a maximum of 10% post-tax of their base
      salary. Annual pre-tax contributions may not individually exceed $8,000 in
      2004 under Puerto Rico law. All employee contributions are invested in any
      of the investment funds offered by the Plan at the direction of the
      participating employees.

      After one year of service, the Company contributes to the Plan an amount
      equal to 75% of the participant's pre-tax contributions up to 6% of their
      base salary into the Johnson & Johnson Stock Fund. Beginning in 2003, all 
      participants have the option to elect that the Company matching 
      contribution be invested in the current investment fund mix chosen by the 
      participant.

      INVESTMENT

      Participants may invest in one or more of the nine investment funds
      offered by the Plan. The investment mix chosen by the participant will
      apply to employee and Company matching contributions, if elected. Rollover
      contributions are invested at the election of the participant.

      VESTING

      A participant's account in the Plan, including participant contributions,
      company contributions and earnings thereon, is always fully vested. As a
      result, there are no forfeitures under the Plan.

                                      -4-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

      PAYMENT OF BENEFITS

      Benefits are paid to participants upon termination of employment or
      retirement. Participants can elect to defer payment if account balances
      are greater than $5,000. Distributions are paid either in a lump sum
      payment, or installment payments made on a monthly, quarterly or annual
      basis. Installment payments are made over a period of years selected by
      the participant.

      A participant's account may be distributed to their beneficiaries in lump
      sum or in installments upon the participant's death.

      Participants are allowed to withdraw their post-tax contributions and
      earnings thereon one time per calendar year. Participants may withdraw
      pre-tax contributions only upon meeting certain hardship conditions. The
      benefits to which participants are entitled are the amounts provided by
      contributions and investment earnings thereon, including realized and
      unrealized gains and losses which have been allocated to the participant's
      account balance. Participants have the option of receiving part of their
      balance in the Johnson & Johnson Stock Fund as either cash or in shares of
      Johnson & Johnson common stock (plus cash for fractional shares) for
      distributions other than a hardship.

      ADMINISTRATIVE EXPENSES

      All third party administrative expenses are paid by the Plan, unless
      otherwise provided for by the Company.

      TERMINATION

      Although it has not expressed an intent to do so, the Company has the
      right under the Plan to discontinue its contributions at any time and to
      terminate the Plan subject to the provisions of ERISA. In the event of a
      partial or full Plan termination, all Plan funds must be used exclusively
      for the benefit of the Plan participants.

2.    SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

      BASIS OF ACCOUNTING

      The financial statements of the Plan are prepared under the accrual method
      of accounting in accordance with accounting principles generally accepted
      in the United States of America.

      INVESTMENT VALUATION AND INCOME RECOGNITION

      The Plan's interest in the Trust is stated at fair value. Generally, it
      represents securities traded on a national securities exchange, which are
      valued at the last reported sales price on the last business day of the
      year. Securities not traded on a national securities exchange are valued
      using external pricing vendors based on the frequency of their valuations.
      Benefit responsive guaranteed and synthetic investment contracts are
      recorded at contract value, which approximates fair value (Note 4).

      As the investment funds contain various underlying assets such as stock
      and short-term investments, the participant's account balance is reported
      in units of participation, which allows for immediate transfers in and out
      of the funds. The purchase or redemption price of the units is determined
      by State Street, based on the current market value of the underlying
      assets of the funds. Each fund's net asset value is the value of a single
      unit, which is computed by adding the value of the fund's investments,
      cash and other assets, and subtracting liabilities, then dividing the
      result by the number of units outstanding.

      Purchases and sales of securities are recorded on a trade-date basis.
      Gains and losses on the sale of investment securities are determined on
      the average cost method. Dividend income is recorded on the ex-dividend
      date. Interest income is recorded as earned on an accrual basis.

                                      -5-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

      NET APPRECIATION (DEPRECIATION)

      The Plan presents in the Statement of Changes in Net Assets Available for
      Benefits the Plan's interest in the Trust and includes net appreciation 
      (depreciation) in the fair value of investments held in the Trust, which 
      consists of unrealized appreciation (depreciation) of the underlying 
      investments and realized gains and losses on sales of
      investments.

      PAYMENT OF BENEFITS 

      Benefits are recorded when paid.

      USE OF ESTIMATES

      The preparation of the Plan's financial statements in conformity with
      generally accepted accounting principles requires management to make
      estimates and assumptions that affect the reported amounts of net assets
      available for benefits at the date of the financial statements and the
      changes in net assets available for benefits during the reporting period
      and, when applicable, disclosures of contingent assets and liabilities at
      the date of the financial statements. Actual results could differ from
      those estimates.

      RISK AND UNCERTAINTIES

      The Plan provides for various investment options in funds which can
      invest in equity and fixed income securities. Investments are exposed to
      various risks, such as interest rate, market and credit. Due to the level
      of risk associated with certain investments, it is at least reasonably
      possible that changes in risks in the near term could materially affect
      participants' account balances and the amounts reported in the Statements
      of Net Assets Available for Benefits and the Statement of Changes in Net
      Assets Available for Benefits.

      RECLASSIFICATION

      Certain prior year amounts have been reclassified to conform to the
      current year presentation.

                                      -6-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

3.    INVESTMENTS IN PLAN MASTER TRUST

      Effective January 1, 2003, the assets of the Plan are maintained in the
      Johnson & Johnson Pension and Savings Plans Master Trust. The Plan holds
      approximately 1.27% and 1.17%, respectively of the Trust's net assets as
      of December 31, 2004 and 2003.

      Net assets, income, and expenses are allocated to the Plan based on the
      total of each participant's share in the respective funds.

      The following table represents the total value of investments in the
      Trust:



                                                                    AS OF DECEMBER 31,
                                                           ------------------------------------
                                                                 2004                2003
                                                                         
Investments at fair value
  Short term investment funds                              $    551,013,386    $    251,872,480
  U.S. Government and Agency securities                         856,971,117         688,955,151
  Corporate debt                                                313,196,278         305,698,696
  Preferred stocks                                               11,061,328          10,536,822
  Common stocks                                               6,822,053,563       4,890,705,529
  Equities and other                                          1,348,404,513       2,074,484,099
Investments at contract value
  Deposits in group annuity contracts and synthetic GICs        973,552,848         924,152,802
                                                           ----------------    ----------------

    Total Master Trust investments                           10,876,253,033       9,146,405,579

Receivables                                                      75,006,869         179,120,628
Liabilities                                                    (211,812,708)       (230,499,957)
                                                           ----------------    ----------------

    Net assets held in Master Trust, at fair value         $ 10,739,447,194    $  9,095,026,250
                                                           ----------------    ----------------


                                       -7-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

      The net investment income of the Johnson & Johnson Pension and Savings
      Plans Master Trust was composed of the following:



                                                   FOR THE
                                                  YEAR ENDED
                                                 DECEMBER 31,
                                                     2004
                                             
Net appreciation in fair value of investments
    Short term investment funds                 $      326,060
    U.S. Government and Agency securities            3,465,629
    Corporate debt                                   8,776,223
    Preferred stocks                                   579,384
    Common stocks                                1,094,390,127
    Equities and other                              39,969,617
                                                --------------

                                                 1,147,507,040
                                                --------------

Interest                                            96,085,856
Dividends                                          101,802,719
                                                --------------

      Net investment gain                       $1,345,395,615
                                                --------------


4.    GUARANTEED AND SYNTHETIC INVESTMENT CONTRACTS

      The Trust holds investments in guaranteed and synthetic investment
      contracts. These investments are recorded at their contract values. This
      represents cost plus accrued interest of guaranteed investment contracts
      and fair value of the collateral plus the benefit responsive wrap value
      for synthetics, as the contracts are fully benefit-responsive.
      Participants may ordinarily direct the withdrawal or transfer of all or a
      portion of their investment at contract value. There are currently no
      reserves against contract values for credit risk of the contract issuers
      or otherwise.

      The average yield of these contracts was approximately 4.12% and 4.86% for
      2004 and 2003, respectively. The crediting interest rate was approximately
      4.22% and 4.96% for 2004 and 2003, respectively. The crediting interest
      rate of the contracts is the annual return of the contracts before plan
      expenses, while the average yield includes plan expenses. The crediting
      interest rate for the investment contracts is either agreed upon in
      advance with the issuer or varies based on an agreed upon formula, but
      cannot be less than zero. The fair value of guaranteed and synthetic
      investment contracts at December 31, 2004 and 2003 was $4,940,892 and
      $4,841,473, respectively.

5.    TAX STATUS

      The Associated Free State of Puerto Rico, Property Department, has
      determined and informed the Company by a letter dated March 1, 1990, that
      the Plan constitutes as a qualified plan under Section 165(a) of the
      Puerto Rico Income Tax Act of 1954 as amended (the "ITA"), and the Plan
      and the related trust accounts are exempt from Puerto Rico income taxes
      under Section 165(a) and 165(e) of the ITA. Although the Plan has been
      amended since receiving the determination letter, the Plan Administrator
      and the Plan's tax counsel believe that the Plan is currently designed and
      is currently being operated in compliance with the applicable requirements
      of the Puerto Rico tax code. Therefore, no provision for income taxes has 

                                      -8-


JOHNSON & JOHNSON
RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------

      been included in the Plan's financial statements.

6.    RELATED PARTY TRANSACTIONS

      Certain Plan investments are shares of mutual funds managed by State
      Street Global Advisors. State Street is the agent trustee as defined by
      the Plan and, therefore, these transactions qualify as party-in-interest
      transactions.

      The Plan also invests in shares of the Company. The Company is the plan
      sponsor and, therefore, these transactions qualify as party-in-interest
      transactions.

7.    RECONCILIATION OF FINANCIAL STATEMENTS TO FORM 5500

      The following is a reconciliation of net assets available for benefits per
      the financial statements to the Form 5500:



                                                               DECEMBER 31,
                                                          2004             2003
                                                                 
Net assets available for benefits
    per the financial statements                      $ 136,304,303    $ 106,763,540
Amounts allocated to withdrawing participants                (8,274)         (17,016)
                                                      -------------    -------------

Net assets available for benefits per the Form 5500   $ 136,296,029    $ 106,746,524
                                                      =============    =============




                                                              FOR THE YEAR ENDED
                                                               DECEMBER 31, 2004
                                                           
Benefits paid to participants per the financial statements       $ 10,025,320

Add: Amounts allocated to withdrawing participants at
    December 31, 2004                                                   8,274

Less: Amounts allocated to withdrawing participants
    at December 31, 2003                                              (17,016)
                                                                 ------------

Benefits paid to participants per the Form 5500                  $ 10,016,578
                                                                 ------------


      Amounts allocated to the withdrawing participants are recorded on the Form
      5500 for benefit payments that have been processed and approved for
      payment prior to December 31, 2004 but not yet paid as of that date.

                                      -9-