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PURE BIOSCIENCE
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PURE BIOSCIENCE

** IMPORTANT NOTICE **
Regarding the Availability of Proxy Materials

You are receiving this communication because you hold shares in the above company, and the materials you should review before you cast your vote are now available.

This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. We encourage you to access and review all of the important information contained in the proxy materials before voting.

PURE BIOSCIENCE
1725 GILLESPIE WAY
EL CAJON, CA 92020

Shareholder Meeting to be held on 01/20/09

Proxy Materials Available

  Notice and Proxy Statement
  Annual Report

PROXY MATERIALS — VIEW OR RECEIVE

You can choose to view the materials online or receive a paper or e-mail copy. There is NO charge for requesting a copy. Requests, instructions and other inquiries will NOT be forwarded to your investment advisor. To facilitate timely delivery please make the request as instructed below on or before 01/06/09.

HOW TO VIEW MATERIALS VIA THE INTERNET

Have the 12 Digit Control Number(s) available and visit www.proxyvote.com

HOW TO REQUEST A COPY OF MATERIALS

    1)        BY INTERNET  -  www.proxyvote.com

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*If requesting materials by e-mail, please send a blank e-mail with the 12 Digit Control Number (located on the following page) in the subject line.


Meeting Information

Meeting Type: Annual

Meeting Date: 01/20/09

Meeting Time: 2:00 P.M. PST

For holders as of: 12/02/2008

Meeting Location

Doubletree Hotel Mission Valley
7450 Hazard Center Drive
San Diego, CA 92108

Meeting Directions:

For Meeting Directions, Please Call:
619-297-5466

How to Vote

Vote In Person

Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the Meeting you will need to request a ballot to vote these shares.

Vote By Internet

To vote now by Internet, go to WWW.PROXYVOTE.COM. Use the Internet to transmit your voting instructions and for electronic delivery of information up until 11:59 P.M. Eastern Time the day before the cut-off date or meeting date. Have your notice in hand when you access the web site and follow the instructions.


Voting items

THE BOARD OF DIRECTORS RECOMMENDSA VOTE “FOR” ITEMS 1 and 2

  1. ELECTION OF DIRECTORS

  01) Gregory H. Barnhill
  02) Dennis Brovarone
  03) Murray H. Gross
  04) Michael L. Krall
  05) Paul V. Maier
  06) Donna Singer
  07) Tommy G. Thompson

  2. Proposal to ratify the appointment of Mayer Hoffman McCann P.C. as PURE Bioscience’s independent registered public accounting firm for the fiscal year ending July 31, 2009