SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G


                    Under the Securities Exchange Act of 1934
                          (Amendment No._____1______)*



                      Interneuron Pharmaceuticals, Inc.
              -----------------------------------------------------
                               (Name of Issuer)


                        Common Stock, $.001 par value
          -------------------------------------------------------------
                         (Title of Class of Securities)


                                 460573108
              -----------------------------------------------------
                               (CUSIP Number)

                             December 21, 2001
                ---------------------------------------------
                              (Date of Event)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

[  ] Rule 13d-1(b)

[XX] Rule 13d-1(c)

[  ] Rule 13d-1(d)


*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).





                              Page 1 of 6 pages





CUSIP No. 460573108                13G                    Page 2 of 6 Pages



--------------------------------------------------------------------------------
   1   NAME OF REPORTING PERSON
       S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

      Dov Perlysky


--------------------------------------------------------------------------------
   2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                             (a)  [  ]
                                                             (b)  [  ]


--------------------------------------------------------------------------------
   3   SEC USE ONLY




--------------------------------------------------------------------------------
   4   CITIZENSHIP OR PLACE OF ORGANIZATION


         United States

--------------------------------------------------------------------------------
   NUMBER OF      5    SOLE VOTING POWER
     SHARES            2,259,981
  BENEFICIALLY    --------------------------------------------------------------
    OWNED BY      6    SHARED VOTING POWER
      EACH             10,000
  REPORTING       --------------------------------------------------------------
     PERSON       7    SOLE DISPOSITIVE POWER
      WITH             2,259,981
                  --------------------------------------------------------------
                  8    SHARED DISPOSITIVE POWER
                       10,000

--------------------------------------------------------------------------------
   9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON


                       2,269,981
--------------------------------------------------------------------------------
  10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*



--------------------------------------------------------------------------------
  11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)


                       4.9%
--------------------------------------------------------------------------------
  12   TYPE OF REPORTING PERSON*


                      IN
--------------------------------------------------------------------------------
                     *SEE INSTRUCTIONS BEFORE FILLING OUT




CUSIP No. 460573108                13G                    Page 3 of 6 Pages



--------------------------------------------------------------------------------
   1   NAME OF REPORTING PERSON
       S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

      Laya Perlysky


--------------------------------------------------------------------------------
   2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                             (a)  [  ]
                                                             (b)  [  ]


--------------------------------------------------------------------------------
   3   SEC USE ONLY




--------------------------------------------------------------------------------
   4   CITIZENSHIP OR PLACE OF ORGANIZATION


         United States

--------------------------------------------------------------------------------
   NUMBER OF      5    SOLE VOTING POWER
     SHARES            2,259,981
  BENEFICIALLY    --------------------------------------------------------------
    OWNED BY      6    SHARED VOTING POWER
      EACH             10,000
  REPORTING       --------------------------------------------------------------
     PERSON       7    SOLE DISPOSITIVE POWER
      WITH             2,259,981
                  --------------------------------------------------------------
                  8    SHARED DISPOSITIVE POWER
                       10,000

--------------------------------------------------------------------------------
   9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON


                       2,269,981
--------------------------------------------------------------------------------
  10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*



--------------------------------------------------------------------------------
  11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)


                       4.9%
--------------------------------------------------------------------------------
  12   TYPE OF REPORTING PERSON*


                      IN
--------------------------------------------------------------------------------
                     *SEE INSTRUCTIONS BEFORE FILLING OUT



                                                        Page 4 of 6 Pages
Item 1.
         (a)   Name of Issuer:
               Interneuron Pharmaceuticals, Inc.

         (b)   Address of Issuer's Principal Executive Offices:
               One Ledgemont Center
               99 Hayden Avenue
               Lexington, MA  02421


Item 2.
         (a)   Name of Person Filing:

               This statement is filed on behalf of Dov Perlysky ("Dov")
               and Laya Perlysky ("Laya") (together, the "Reporting Parties").


         (b)   Address of Principal Business Office:

               The Reporting Parties address is 8 Lakeside Drive West, Lawrence,
               New York 11559.


         (c)   Citizen:

               Both are citizens of the United States.

         (d)   Title of Class of Securities:
               Common Stock, $.001 par value ("shares").

         (e)   CUSIP#:
               460573108


Item 3.     If this statement  is filed  pursuant to Rules  13d-1(b), or
            13d-2(b), check whether the person filing is a:

            (a)   [ ]   Broker or Dealer  registered under Section  15 of  the
                        Act

            (b)   [ ]   Bank as defined in section 3(a)(6) of the Act

            (c)   [ ]   Insurance Company  as defined  in section  3(a)(19) of
                        the Act

            (d)   [ ]   Investment Company registered under  section 8 of  the
                        Investment Company Act of 1940

            (e)   [ ]   An investment adviser in accordance with 240.13d-1
                        (b)(1)(ii)(E)

            (f)   [ ]   An employee benefit Plan or endowment fund in
                        accordance with 240.13d-1(b)(1)(ii)(F)

            (g)   [ ]   A parent holding Company or control person in
                        accordance  with  240.13d-1(b)(1)(ii)(G)

            (h)   [ ]   A savings associations as defined in Section 3(b) of
                        the Federal Deposit Insurance Act

            (i)   [ ]   A church plan that is excluded from definition of an
                        investment company under section 3(c)(14) of the
                        Investment Company Act of 1940.



 
                                                        Page 5 of 6 Pages
Item 4.   Ownership:

   (a)(b) The  Reporting  Parties  may  each be  deemed  to  beneficially  own
          2,269,981  shares  or 4.9% of the  Issuer's  shares  as  follows:  (i)
          1,719,000  shares owned  directly by Dov Perlysky,  (ii) 10,000 shares
          owned by a charitable entity controlled by the Reporting Parties,  and
          (iii) 540,981 shares owned directly by Laya Perlysky (1).


      (c) Dov has sole voting and dispositive control of shares owned by him.
          Laya has sole voting and dispositive power over shares owned directly
          by her.  Both have the voting and dispositive control over shares
          owned by the charitable entity.


Item 5.   Ownership of Five Percent or Less of a Class:

           The Reporting Parties own less than five percent.


Item 6.   Ownership of More than Five Percent on Behalf of Another Person:

                Not applicable.


Item 7.   Identification and Classification of the Subsidiary Which
          Acquired the Security Being Reported on By the Parent Holding
          Company:

              Not  applicable.



Item 8.    Identification and Classification of Members of the Group:

             Not applicable.




__________________________________________________________________________

(1)  Dov and Laya Perlysky are husband and wife.  Filing of this statement shall
     not be deemed an  admission  by Dov  Perlysky  or Laya  Perlysky  that they
     beneficially  own the  securities  attributed  to the  other  for any other
     purpose.  They expressly  disclaim  beneficial  ownership of all securities
     held by each other.



Item 9.     Notice of Dissolution of Group:

            Not applicable.


Item 10. Certification: By signing below, we certify that to the best of our
         knowledge  and belief,  the  securities  referred to above were
         acquired in the ordinary  course  of  business  and were not  acquired
         and are not held for the purpose of and do not have the effect of
         changing or influencing  the control of the issuer of such  securities
         and were not acquired and are not held in  connection  with or as
         participant in any transaction having such purpose of effect.


                                   SIGNATURES

         After  reasonable  inquiry and to the best  knowledge and belief of the
Reporting Persons, each such person or entity certifies that the information set
forth in this statement is true, complete and correct.






Dated:   January 3, 2002                  /s/ Dov Perlysky
         New York, New York             _____________________________
                                             Dov Perlysky








Dated:   January 3, 2002                /s/ Laya Perlysky
         New York, New York             _____________________________
                                             Laya Perlysky