Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Weiner David B.
 2. Date of Event Requiring Statement (Month/Day/Year)
03/09/2016		 3. Issuer Name and Ticker or Trading Symbol
INOVIO PHARMACEUTICALS, INC. [INO]
(Last)
(First)
(Middle)
660 W. GERMANTOWN PIKE, SUITE 100		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

PLYMOUTH MEETING, PA 19462		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 723,622
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Common Stock Option 09/30/2009 09/30/2019 Common Stock 15,000 $ 6.28 D  
Common Stock Option 03/11/2011 03/11/2021 Common Stock 17,500 $ 4.56 D  
Common Stock Options 02/23/2012 02/23/2022 Common Stock 22,500 $ 2.4 D  
Common Stock Option 03/14/2013(1) 03/14/2023 Common Stock 23,750 $ 2.16 D  
Common Stock Options 03/26/2014(2) 03/26/2024 Common Stock 18,750 $ 12.92 D  
Common Stock Option 05/22/2014(3) 05/22/2024 Common Stock 18,750 $ 8.8 D  
Common Stock Option 03/05/2015(4) 03/05/2025 Common Stock 85,000 $ 7.56 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Weiner David B.
660 W. GERMANTOWN PIKE
SUITE 100
PLYMOUTH MEETING, PA 19462		   X      

Signatures

/s/ David B. Weiner 03/11/2016
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) 17,812 shares have vested, the remaining 5,938 vest on March 14, 2016.
(2) 9,374 shares have vested; 4,688 vest on March 26, 2016 and 4,688 vest on March 26, 2017.
(3) 9,375 shares have vested; 4,687 vest on May 22, 2016 and 4,688 vest on May 22, 2017.
(4) 42,500 shares have vested; 21,250 vest on March 5, 2017 and 21,250 vest on March 5, 2018.

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