Form N-Q

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM N-Q


QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number         811-21213         

        Nuveen Insured Tax-Free Advantage Municipal Fund         
(Exact name of registrant as specified in charter)


        333 West Wacker Drive, Chicago, Illinois 60606         
(Address of principal executive offices) (Zip code)


Jessica R. Droeger—Vice President and Secretary
        333 West Wacker Drive, Chicago, Illinois 60606         
(Name and address of agent for service)

Registrant's telephone number, including area code:         312-917-7700        

Date of fiscal year end:            10/31          

Date of reporting period:          1/31/06         

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-5 (§§ 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b1-5 under the Investment Company Act of 1940 (17 CFR 270.30b1-5). The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public. A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget (“OMB”) control number. Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609. The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. § 3507.

Item 1. Schedule of Investments

  Portfolio of Investments (Unaudited)
Nuveen Insured Tax-Free Advantage Municipal Fund (NEA)
January 31, 2006

        Optional         
Principal        Call         
Amount (000)    Description (1)    Provisions (2)    Ratings (3)    Value 
    Alabama – 8.3% (5.5% of Total Investments)             
$     5,655    Colbert County-Northwest Health Care Authority, Alabama, Revenue Bonds, Helen Keller Hospital,    6/13 at 101.00    Baa3   $   5,810,739 
     Series 2003, 5.750%, 6/01/27             
3,100    Huntsville Healthcare Authority, Alabama, Revenue Bonds, Series 1998A, 5.400%, 6/01/22 – MBIA    5/12 at 102.00    AAA    3,374,753 
     Insured             
6,280    Jefferson County, Alabama, Sewer Revenue Capital Improvement Warrants, Series 2002D, 5.000%,    8/12 at 100.00    AAA    6,786,294 
     2/01/32 (Pre-refunded 8/01/12) – FGIC Insured             
1,750    Montgomery, Alabama, General Obligation Warrants, Series 2003, 5.000%, 5/01/21 – AMBAC Insured    5/12 at 101.00    AAA    1,847,930 
4,500    Sheffield, Alabama, Electric Revenue Bonds, Series 2003, 5.500%, 7/01/29 – AMBAC Insured    7/13 at 100.00    Aaa    4,898,520 
21,285    Total Alabama            22,718,236 
    Arizona – 3.8% (2.5% of Total Investments)             
10,000    Maricopa County Pollution Control Corporation, Arizona, Revenue Bonds, Arizona Public Service    11/12 at 100.00    AAA    10,335,800 
     Company – Palo Verde Project, Series 2002A, 5.050%, 5/01/29 – AMBAC Insured             
    California – 29.0% (19.2% of Total Investments)             
26,300    California State Public Works Board, Lease Revenue Bonds, Department of General Services,    12/12 at 100.00    AAA    27,197,619 
     Capital East End Project, Series 2002A, 5.000%, 12/01/27 – AMBAC Insured             
7,500    California, General Obligation Bonds, Series 2004, 5.000%, 4/01/31 – AMBAC Insured    4/14 at 100.00    AAA    7,771,650 
13,500    California, General Obligation Refunding Bonds, Series 2002, 5.250%, 4/01/30 – XLCA Insured    4/12 at 100.00    AAA    14,317,965 
2,910    Cathedral City Public Financing Authority, California, Tax Allocation Bonds, Housing    8/12 at 102.00    AAA    3,033,762 
     Set-Aside, Series 2002D, 5.000%, 8/01/26 – MBIA Insured             
2,500    Irvine Public Facilities and Infrastructure Authority, California, Assessment Revenue Bonds,    3/06 at 103.00    AAA    2,575,600 
     Series 2003C, 5.000%, 9/02/23 – AMBAC Insured             
4,000    Montara Sanitation District, California, General Obligation Bonds, Series 2003, 5.000%,    8/11 at 101.00    AAA    4,156,560 
     8/01/28 – FGIC Insured             
    Plumas County, California, Certificates of Participation, Capital Improvement Program, Series             
    2003A:             
1,130     5.250%, 6/01/19 – AMBAC Insured    6/13 at 101.00    AAA    1,224,773 
1,255     5.250%, 6/01/21 – AMBAC Insured    6/13 at 101.00    AAA    1,353,618 
1,210    Redding Joint Powers Financing Authority, California, Lease Revenue Bonds, Capital Improvement    3/13 at 100.00    AAA    1,255,206 
     Projects, Series 2003A, 5.000%, 3/01/23 – AMBAC Insured             
3,750    Sacramento Municipal Utility District, California, Electric Revenue Bonds, Series 2003R,    8/13 at 100.00    AAA    3,903,938 
     5.000%, 8/15/28 – MBIA Insured             
1,500    San Diego Community College District, California, General Obligation Bonds, Series 2003A,    5/13 at 100.00    AAA    1,559,505 
     5.000%, 5/01/28 – FSA Insured             
3,000    San Jose Redevelopment Agency, California, Tax Allocation Bonds, Merged Area Redevelopment    8/10 at 101.00    AAA    3,067,080 
     Project, Series 2002, 5.000%, 8/01/32 – MBIA Insured             
1,055    Turlock Irrigation District, California, Certificates of Participation, Series 2003A, 5.000%,    1/13 at 100.00    AAA    1,088,865 
     1/01/28 – MBIA Insured             
6,300    University of California, Revenue Bonds, Multi-Purpose Projects, Series 2003A, 5.000%, 5/15/33 –    5/13 at 100.00    AAA    6,499,395 
     AMBAC Insured             
75,910    Total California            79,005,536 
    Colorado – 3.8% (2.5% of Total Investments)             
    Bowles Metropolitan District, Colorado, General Obligation Bonds, Series 2003:             
4,300     5.500%, 12/01/23 – FSA Insured    12/13 at 100.00    AAA    4,736,837 
3,750     5.500%, 12/01/28 – FSA Insured    12/13 at 100.00    AAA    4,114,800 
1,450    Colorado Educational and Cultural Facilities Authority, Charter School Revenue Bonds,    8/14 at 100.00    AAA    1,542,757 
     Peak-to-Peak Charter School, Series 2004, 5.250%, 8/15/24 – XLCA Insured             
9,500    Total Colorado            10,394,394 
    Florida – 1.2% (0.8% of Total Investments)             
3,000    Pinellas County Health Facilities Authority, Florida, Revenue Bonds, Baycare Health System,    5/13 at 100.00    A1    3,170,130 
     Series 2003, 5.500%, 11/15/27             
    Georgia – 1.5% (1.0% of Total Investments)             
3,825    Metropolitan Atlanta Rapid Transit Authority, Georgia, Sales Tax Revenue Bonds, Second    1/13 at 100.00    AAA    3,957,001 
     Indenture Series 2002, 5.000%, 7/01/32 – MBIA Insured             
    Illinois – 3.8% (2.5% of Total Investments)             
905    Cook County School District 100, Berwyn South, Illinois, General Obligation Refunding Bonds,    12/13 at 100.00    Aaa    997,328 
     Series 2003B, 5.250%, 12/01/21 (Pre-refunded 12/01/13) – FSA Insured             
    Cook County School District 145, Arbor Park, Illinois, General Obligation Bonds, Series 2004:             
3,285     5.125%, 12/01/20 – FSA Insured    12/14 at 100.00    Aaa    3,521,421 
2,940     5.125%, 12/01/23 – FSA Insured    12/14 at 100.00    Aaa    3,124,955 
2,500    Illinois Health Facilities Authority, Revenue Bonds, Lake Forest Hospital, Series 2003,    7/13 at 100.00    A–    2,585,950 
     5.250%, 7/01/23             
9,630    Total Illinois            10,229,654 
    Indiana – 8.8% (5.8% of Total Investments)             
2,500    Evansville, Indiana, Sewerage Works Revenue Refunding Bonds, Series 2003A, 5.000%, 7/01/23 –    7/13 at 100.00    AAA    2,622,025 
     AMBAC Insured             
2,190    Indiana Bond Bank, Advance Purchase Funding Bonds, Common School Fund, Series 2003B, 5.000%,    8/13 at 100.00    AAA    2,306,771 
     8/01/19 – MBIA Insured             
1,000    Indiana University, Student Fee Revenue Bonds, Series 2003O, 5.000%, 8/01/22 – FGIC Insured    8/13 at 100.00    AAA    1,049,700 
    IPS Multi-School Building Corporation, Indiana, First Mortgage Revenue Bonds, Series 2003:             
11,020     5.000%, 7/15/19 – MBIA Insured    7/13 at 100.00    AAA    11,673,927 
6,000     5.000%, 7/15/20 – MBIA Insured    7/13 at 100.00    AAA    6,332,700 
22,710    Total Indiana            23,985,123 
    Kansas – 2.4% (1.6% of Total Investments)             
6,250    Kansas Development Finance Authority, Board of Regents, Revenue Bonds, Scientific Research and    4/13 at 102.00    AAA    6,623,125 
     Development Facilities Projects, Series 2003C, 5.000%, 10/01/22 – AMBAC Insured             
    Kentucky – 0.5% (0.3% of Total Investments)             
    Kentucky State Property and Buildings Commission, Revenue Refunding Bonds, Project 77, Series             
    2003:             
340     5.000%, 8/01/23 (Pre-refunded 8/01/13) – MBIA Insured    8/13 at 100.00    AAA    367,907 
985     5.000%, 8/01/23 (Pre-refunded 8/01/13) – MBIA Insured    8/13 at 100.00    AAA    1,065,849 
1,325    Total Kentucky            1,433,756 
    Louisiana – 2.2% (1.5% of Total Investments)             
5,785    New Orleans, Louisiana, General Obligation Refunding Bonds, Series 2002, 5.300%, 12/01/27 –    12/12 at 100.00    AAA    6,080,324 
     FGIC Insured             
    Massachusetts – 5.1% (3.4% of Total Investments)             
9,000    Massachusetts Bay Transportation Authority, Senior Sales Tax Revenue Refunding Bonds, Series    7/12 at 100.00    AAA    9,718,560 
     2002A, 5.000%, 7/01/27 (Pre-refunded 7/01/12) – FGIC Insured             
1,125    Massachusetts Development Finance Authority, Revenue Bonds, Middlesex School, Series 2003,    9/13 at 100.00    A1    1,177,065 
     5.125%, 9/01/23             
3,000    Massachusetts Turnpike Authority, Metropolitan Highway System Revenue Bonds, Senior Series    1/07 at 102.00    AAA    3,045,780 
     1997A, 5.000%, 1/01/37 – MBIA Insured             
13,125    Total Massachusetts            13,941,405 
    Michigan – 11.6% (7.7% of Total Investments)             
6,130    Detroit, Michigan, Senior Lien Water Supply System Revenue Bonds, Series 2003A, 5.000%,    7/13 at 100.00    AAA    6,459,488 
     7/01/23 – MBIA Insured             
4,465    Detroit, Michigan, Senior Lien Water Supply System Revenue Refunding Bonds, Series 2003C,    7/13 at 100.00    AAA    4,706,467 
     5.000%, 7/01/22 – MBIA Insured             
10,800    Michigan Strategic Fund, Limited Obligation Resource Recovery Revenue Refunding Bonds, Detroit    12/12 at 100.00    AAA    11,261,376 
     Edison Company, Series 2002D, 5.250%, 12/15/32 – XLCA Insured             
2,250    Romulus Community Schools, Wayne County, Michigan, General Obligation Refunding Bonds, Series    5/11 at 100.00    AA    2,387,655 
     2001, 5.250%, 5/01/25             
6,500    Wayne County, Michigan, Limited Tax General Obligation Airport Hotel Revenue Bonds, Detroit    12/11 at 101.00    AAA    6,733,480 
     Metropolitan Wayne County Airport, Series 2001A, 5.000%, 12/01/30 – MBIA Insured             
30,145    Total Michigan            31,548,466 
    Missouri – 1.1% (0.7% of Total Investments)             
    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series 2004:             
1,325     5.250%, 3/01/23 – FSA Insured    3/14 at 100.00    AAA    1,444,502 
1,500     5.250%, 3/01/24 – FSA Insured    3/14 at 100.00    AAA    1,632,465 
2,825    Total Missouri            3,076,967 
    Nebraska – 1.9% (1.3% of Total Investments)             
5,000    Lincoln, Nebraska, Sanitary Sewerage System Revenue Refunding Bonds, Series 2003, 5.000%,    6/13 at 100.00    AAA    5,198,050 
     6/15/28 – MBIA Insured             
    Nevada – 0.9% (0.6% of Total Investments)             
2,315    Clark County, Nevada, Subordinate Lien Airport Revenue Bonds, Series 2001B, 5.200%, 7/01/31    7/11 at 100.00    AAA    2,503,441 
     (Pre-refunded 7/01/11) – FGIC Insured             
    New Mexico – 0.8% (0.5% of Total Investments)             
1,975    New Mexico State University, Revenue Bonds, Series 2004, 5.000%, 4/01/19 – AMBAC Insured    4/14 at 100.00    AAA    2,100,729 
    New York – 10.2% (6.8% of Total Investments)             
25,000    Metropolitan Transportation Authority, New York, Transportation Revenue Refunding Bonds,    11/12 at 100.00    AAA    25,848,250 
     Series 2002F, 5.000%, 11/15/31 – MBIA Insured             
1,850    New York State Urban Development Corporation, Service Contract Revenue Bonds, Series 2005B,    3/15 at 100.00    AAA    1,951,787 
     5.000%, 3/15/25 – FSA Insured             
26,850    Total New York            27,800,037 
    North Carolina – 3.3% (2.2% of Total Investments)             
8,700    North Carolina Medical Care Commission, Revenue Bonds, Maria Parham Medical Center, Series    10/13 at 100.00    AA    9,102,288 
     2003, 5.375%, 10/01/33 – RAAI Insured             
    Oklahoma – 0.5% (0.2% of Total Investments)             
1,000    Oklahoma Capitol Improvement Authority, State Facilities Revenue Bonds, Series 2005F, 5.000%,    7/15 at 100.00    AAA    1,057,270 
     7/01/24 – AMBAC Insured             
    Oregon – 3.6% (2.4% of Total Investments)             
9,350    Oregon Health Sciences University, Revenue Bonds, Series 2002A, 5.000%, 7/01/32 – MBIA Insured    1/13 at 100.00    AAA    9,678,279 
    Pennsylvania – 8.7% (5.8% of Total Investments)             
3,000    Lehigh County General Purpose Authority, Pennsylvania, Hospital Revenue Bonds, St. Luke’s    8/13 at 100.00    Baa1    3,091,710 
     Hospital of Bethlehem, Series 2003, 5.375%, 8/15/33             
2,000    Philadelphia Gas Works, Pennsylvania, Revenue Bonds, General Ordinance, Fourth Series 1998,    8/13 at 100.00    AAA    2,063,700 
     5.000%, 8/01/32 – FSA Insured             
925    Philadelphia, Pennsylvania, Water and Wastewater Revenue Bonds, Series 1997A, 5.125%, 8/01/27 –    8/07 at 102.00    AAA    954,896 
       (ETM) AMBAC Insured             
4,075    Philadelphia, Pennsylvania, Water and Wastewater Revenue Bonds, Series 1997A, 5.125%, 8/01/27 –    8/07 at 102.00    AAA    4,234,088 
     AMBAC Insured             
13,000    State Public School Building Authority, Pennsylvania, Lease Revenue Bonds, Philadelphia School    6/13 at 100.00    AAA    13,413,660 
     District, Series 2003, 5.000%, 6/01/33 – FSA Insured             
23,000    Total Pennsylvania            23,758,054 
    South Carolina – 7.4% (4.9% of Total Investments)             
5,000    Florence County, South Carolina, Hospital Revenue Bonds, McLeod Regional Medical Center,    11/14 at 100.00    AAA    5,361,850 
     Series 2004A, 5.250%, 11/01/23 – FSA Insured             
    Greenville County School District, South Carolina, Installment Purchase Revenue Bonds, Series 2003:             
3,000     5.000%, 12/01/22    12/13 at 100.00    AA-    3,109,950 
1,785     5.000%, 12/01/23    12/13 at 100.00    AA-    1,846,832 
1,365    Myrtle Beach, South Carolina, Water and Sewerage System Revenue Refunding Bonds, Series 2003,    3/13 at 100.00    AAA    1,488,956 
     5.375%, 3/01/19 – FGIC Insured             
8,000    South Carolina Transportation Infrastructure Bank, Revenue Bonds, Series 2002A, 5.000%,    10/12 at 100.00    Aaa    8,243,920 
     10/01/33 – AMBAC Insured             
19,150    Total South Carolina            20,051,508 
    Texas – 13.0% (8.6% of Total Investments)             
7,975    Fort Bend Independent School District, Fort Bend County, Texas, General Obligation Bonds,    8/10 at 100.00    AAA    8,283,074 
     Series 2000, 5.000%, 8/15/25             
12,500    Grand Prairie Independent School District, Dallas County, Texas, General Obligation Bonds,    2/13 at 100.00    AAA    12,966,625 
     Series 2003, 5.125%, 2/15/31 – FSA Insured             
2,000    Houston, Texas, First Lien Combined Utility System Revenue Bonds, Series 2004A, 5.250%,    5/14 at 100.00    AAA    2,136,200 
     5/15/25 – MBIA Insured             
5,515    Houston, Texas, General Obligation Refunding Bonds, Series 2002, 5.250%, 3/01/20 – MBIA Insured    3/12 at 100.00    AAA    5,916,106 
5,850    Katy Independent School District, Harris, Fort Bend and Waller Counties, Texas, General    2/12 at 100.00    AAA    6,227,325 
     Obligation Bonds, Series 2002A, 5.125%, 2/15/18             
33,840    Total Texas            35,529,330 
    Virginia – 0.6% (0.4% of Total Investments)             
1,500    Hampton, Virginia, Revenue Bonds, Convention Center Project, Series 2002, 5.125%, 1/15/28 –    1/13 at 100.00    AAA    1,566,345 
     AMBAC Insured             
    Washington – 9.2% (6.1% of Total Investments)             
4,945    Broadway Office Properties, King County, Washington, Lease Revenue Bonds, Washington Project,    12/12 at 100.00    AAA    5,084,350 
     Series 2002, 5.000%, 12/01/31 – MBIA Insured             
5,250    Chelan County Public Utility District 1, Washington, Hydro Consolidated System Revenue Bonds,    7/12 at 100.00    AAA    5,419,103 
     Series 2002C, 5.125%, 7/01/33 – AMBAC Insured             
2,135    Kitsap County Consolidated Housing Authority, Washington, Revenue Bonds, Bremerton Government    7/13 at 100.00    Aaa    2,225,524 
     Center, Series 2003, 5.000%, 7/01/23 – MBIA Insured             
1,935    Pierce County School District 343, Dieringer, Washington, General Obligation Refunding Bonds,    6/13 at 100.00    Aaa    2,095,624 
     Series 2003, 5.250%, 12/01/17 – FGIC Insured             
9,670    Washington, General Obligation Bonds, Series 2003D, 5.000%, 12/01/21 – MBIA Insured    6/13 at 100.00    AAA    10,168,972 
23,935    Total Washington            24,993,573 
    West Virginia – 1.2% (0.8% of Total Investments)             
3,000    West Virginia State Building Commission, Lease Revenue Refunding Bonds, Regional Jail and    No Opt. Call    AAA    3,380,550 
     Corrections Facility, Series 1998A, 5.375%, 7/01/21 – AMBAC Insured             
    Wisconsin – 6.7% (4.4% of Total Investments)             
1,190    Sun Prairie Area School District, Dane County, Wisconsin, General Obligation Bonds, Series    3/14 at 100.00    Aaa    1,274,431 
     2004C, 5.250%, 3/01/24 – FSA Insured             
4,605    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Franciscan Sisters of    9/13 at 100.00    A–    4,902,805 
     Christian Charity Healthcare Ministry, Series 2003A, 5.875%, 9/01/33             
3,000    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Meriter Hospital Inc.,    No Opt. Call    AAA    3,446,910 
     Series 1992A, 6.000%, 12/01/22 – FGIC Insured             
3,600    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Wheaton Franciscan    8/13 at 100.00    A    3,662,964 
     Services Inc., Series 2003A, 5.125%, 8/15/33             
4,750    Wisconsin Health and Educational Facilities Authority, Revenue Refunding Bonds, Wausau    8/08 at 102.00    AAA    4,998,470 
     Hospital Inc., Series 1998A, 5.125%, 8/15/20 – AMBAC Insured             
17,145    Total Wisconsin            18,285,580 
$     392,075    Total Investments (cost $393,026,527) – 151.1%            411,504,951 
    Other Assets Less Liabilities – 1.8%            4,788,214 
    Preferred Shares, at Liquidation Value – (52.9)%            (144,000,000) 
    Net Assets Applicable to Common Shares – 100%           $   272,293,165 

Forward Swaps outstanding at January 31, 2006:

        Fixed Rate        Floating Rate                 
        Paid    Fixed Rate    Received    Floating Rate            Unrealized 
    Notional    by the Fund    Payment    by the Fund    Payment    Effective    Terminiation    Appreciation 
Counterparty    Amount    (annualized)    Frequency    Based On    Frequency    Date (4)    Date    (Depreciation) 
Citigroup    $ 13,500,000    4.652%    Semi-Annually    3 Month USD-LIBOR    Quarterly    2/22/06    2/22/26    $ 826,170 
Citigroup    3,000,000    4.699    Semi-Annually    3 Month USD-LIBOR    Quarterly    2/27/06    2/27/26    166,093 
JPMorgan    9,000,000    5.075    Semi-Annually    3 Month USD-LIBOR    Quarterly    2/22/06    2/22/06    77,172 
                                $1,069,435 

USD-LIBOR (United States Dollar–London Inter–Bank Offered Rates)

    At least 80% of the Fund’s net assets (including net assets attributable to Preferred shares) are invested 
    in municipal securities that are either covered by Original Issue Insurance, Secondary Market Insurance 
    or Portfolio Insurance which ensures the timely payment of principal and interest. Up to 20% of the Fund’s 
    net assets (including net assets attributable to Preferred shares) may be invested in municipal securities 
    that are (i) either backed by an escrow or trust containing sufficient U.S. Government or U.S. Government 
    agency securities (also ensuring the timely payment of principal and interest), or (ii) rated, at the time of 
    investment, within the four highest grades (Baa or BBB or better by Moody’s, S&P or Fitch) or unrated but 
    judged to be of comparable quality by the Adviser. 
(1)    All percentages shown in the Portfolio of Investments are based on net assets applicable to Common 
    shares unless otherwise noted. 
(2)    Optional Call Provisions: Dates (month and year) and prices of the earliest optional call or redemption. 
    There may be other call provisions at varying prices at later dates. Certain mortgage-backed securities 
    may be subject to periodic principal paydowns. 
(3)    Ratings: Using the higher of Standard & Poor’s or Moody’s rating. Ratings below Baa by Moody's Investor 
    Service, Inc. or BBB by Standard & Poor's Group are considered to be below investment grade. 
(4)    Effective date represents that date on which both the Fund and counterparty commence interest payment 
    accruals on each forward swap contract. 
(ETM)    Security is escrowed to maturity. 

Income Tax Information

The following information is presented on an income tax basis. Differences between amounts for financial statement and federal income tax purposes are primarily due to timing differences in recognizing taxable market discount and timing differences in recognizing certain gains and losses on investment transactions.

At January 31, 2006, the cost of investments was $397,033,266.

Gross unrealized appreciation and gross unrealized depreciation of investments at January 31, 2006, were as follows:

Gross unrealized:   
  Appreciation  $18,507,819 
  Depreciation  (4,036,134) 
Net unrealized appreciation (depreciation) of investments  $14,471,685 

Item 2. Controls and Procedures.

  1. The registrant's principal executive and principal financial officers, or persons performing similar functions, have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the "1940 Act") (17 CFR 270.30a-3(c))) are effective, as of a date within 90 days of the filing date of this report that includes the disclosure required by this paragraph, based on their evaluation of the controls and procedures required by Rule 30a-3(b) under the 1940 Act (17 CFR 270.30a-3(b)) and Rule 13a-15(b) or 15d-15(b) under the Securities Exchange Act of 1934 (17 CFR 240.13a-15(b) or 240.15d-15(b)).
  2. There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant's last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 3. Exhibits.

File as exhibits as part of this Form a separate certification for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the 1940 Act (17 CFR 270.30a-2(a)), exactly as set forth below: EX-99 CERT Attached hereto.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)         Nuveen Insured Tax-Free Advantage Municipal Fund        

By (Signature and Title)*          /s/ Jessica R. Droeger                     
                                                    Jessica R. Droeger
                                                    Vice President and Secretary

Date         March 31, 2006        

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)*         /s/ Gifford R. Zimmerman                    
                                                   Gifford R. Zimmerman
                                                   Chief Administrative Officer (principal executive officer) 

Date         March 31, 2006        

By (Signature and Title)*         /s/ Stephen D. Foy                              
                                                   Stephen D. Foy
                                                   Vice President and Controller (principal financial officer) 

Date        March 31, 2006        

* Print the name and title of each signing officer under his or her signature.