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*** Exercise Your Right to Vote *** Important Notice Regarding the Availability of Proxy Materials for the Stockholder Meeting to Be Held on May 10, 2017. Meeting Information GILEAD SCIENCES, INC. Meeting Type: Annual Meeting For holders as of: March 16, 2017 Date: May 10, 2017 Time: 10:00 a.m. Location: Westin San Francisco Airport 1 Old Bayshore Highway Millbrae, CA 94030 You are receiving this communication because you hold shares in the company named above. GILEAD SCIENCES, INC. ATTN: INVESTOR RELATIONS This is not a ballot. You cannot use this notice to vote these 333 LAKESIDE DRIVE FOSTER CITY, CA 94404 shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting. P87169 proxy See the materials reverse and side voting of this instructions. notice to obtain E24415 -



Before You Vote How to Access the Proxy Materials Proxy Materials Available to VIEW or RECEIVE: NOTICE AND PROXY STATEMENT FORM 10-K SUPPLEMENT How to View Online: Have the information that is printed in the box marked by the arrowXXXX XXXX XXXX XXXX (located on the following page) and visit: How to Request and Receive a PAPER or E-MAIL Copy: If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request: 1) BY INTERNET: 2) BY TELEPHONE: 1-800-579-1639 3) BY E-MAIL*: * If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrowXXXX XXXX XXXX XXXX (located on the following page) in the subject line. Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before April 26, 2017 to facilitate timely delivery. How To Vote Please Choose One of the Following Voting Methods Vote In Person: Many stockholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares. Vote By Internet: To vote now by Internet, go to Have the information that is printed in the box—marked by the arrow XXXX XXXX XXXX XXXX (located on the following page) available and follow the instructions. Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card. P87169 E24416



Voting Items The Board of Directors recommends you vote FOR the following proposals: 1. Election of Directors Nominees: 1a. John F. Cogan, Ph.D. 1b. Kelly A. Kramer 1c. Kevin E. Lofton 1d. John C. Martin, Ph.D. 1e. John F. Milligan, Ph.D. 1f. Nicholas G. Moore 1g. Richard J. Whitley, M.D. 1h. Gayle E. Wilson 1i. Per Wold-Olsen 2. Ratification of the Selection of Independent Registered Public Accounting Firm. 3. Restatement of the Gilead Sciences, Inc. 2004 Equity Incentive Plan. 4. Advisory Vote to Approve the Compensation of our Named Executive Officers. The Board of Directors recommends you vote 1 year on the following proposal: 5. Advisory Vote as to the Frequency of Future Advisory Stockholder Votes on Executive Compensation. The Board of Directors recommends you vote AGAINST the following proposals: 6. Stockholder Proposal Requesting that the Board Take Steps to Permit Stockholder Action by Written Consent. 7. Stockholder Proposal Requesting that the Board Adopt a Policy that the Chairman of the Board of Directors be an Independent Director. E24417-P87169