Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  NEW ENTERPRISE ASSOCIATES 10 L P
2. Date of Event Requiring Statement (Month/Day/Year)
03/08/2007
3. Issuer Name and Ticker or Trading Symbol
SOURCEFIRE INC [FIRE]
(Last)
(First)
(Middle)
1119 ST. PAUL STREET
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

BALTIMORE, MD 21202
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series B Convertible Preferred Stock   (1)   (2) Common Stock 2,315,909 $ (3) D (4)  
Series C Convertible Preferred Stock   (1)   (2) Common Stock 576,233 $ (3) D (4)  
Series D Convertible Preferred Stock   (1)   (2) Common Stock 317,418 $ (3) D (4)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
NEW ENTERPRISE ASSOCIATES 10 L P
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
NEA PARTNERS 10 L P
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
BARRIS PETER J
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
BARRETT M JAMES
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
KRAMLICH C RICHARD
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
NEWHALL CHARLES W III
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
PERRY MARK W
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
SANDELL SCOTT D
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    
TRAINOR III EUGENE A
1119 ST. PAUL STREET
BALTIMORE, MD 21202
    X    

Signatures

/s/ Louis S. Citron, attorney-in-fact 03/08/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Convertible at any time.
(2) Not applicable.
(3) Convertible to Common Stock on approximately a 1 to 0.6158 basis.
(4) The shares are directly held by New Enterprise Associates 10, Limited Partnership ("NEA 10") and indirectly held by NEA Partners 10, Limited Partnership ("NEA Partners 10"), the sole general partner of NEA 10, and the individual general partners of NEA Partners 10 (NEA Partners and their general partners together, the "Indirect Reporting Persons"). The general partners of NEA Partners 10, L.P. are Peter Barris, M. James Barrett, C. Richard Kramlich, Charles W. Newhall, III, Mark W. Perry, Scott D. Sandell and Eugene A. Trainor, III. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 10 shares in which the Indirect Reporting Persons have no actual pecuniary interest therein.
 
Remarks:
In addition, NEA Ventures 2003, L.P. owns Series B shares convertible into 7,985 shares of Common Stock of the Issuer.  The Reporting Persons do not have voting nor dispositive power over the shares held by NEA Ventures 2003, L.P.  The Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of those shares in which the Reporting Persons have no actual pecuniary interest therein.

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