UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

___________________

Form 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 

OF THE SECURITIES EXCHANGE ACT OF 1934

For the month of May 2006

Commission File Number 1-32654

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ANORMED INC.

(Translation of registrant's name into English)

#200 – 20353 64^th Avenue

Langley, British Columbia

Canada  V2Y 1N5

(Address of principal executive offices)

___________________

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ___   Form 40-F _X_

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1)  __

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7)  __

Indicate by check mark whether the registrant by furnishing the information contained in this Form is 

also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the 

Securities Exchange Act of 1934.

Yes ___    No  _X_

 

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b):  82-                         .

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DOCUMENTS FILED

See the Exhibit Index hereto for a list of the documents filed herewith and forming a part of this Form 6-K.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

ANORMED INC.

By:

 /s/ William J. Adams    

Name:  William J. (Bill) Adams

Title:

   Chief Financial Officer,
Vice President, Finance, Secretary and Treasurer

Date:  May 26, 2006

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EXHIBIT INDEX

Exhibit	Description
99.1	Material Change Report (Form 51-102F3) dated May 26, 2006.

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Exhibit 99.1

 

FORM 51-102F3

MATERIAL CHANGE REPORT

Item 1. Name and Address of Company

AnorMED Inc. (the “Company”)

Suite 200, 20353 - 64^th Avenue

Langley, British Columbia V2Y 1N5

Item 2. Date of Material Change

May 23, 2006

Item 3. News Release

On May 24, 2006, the Company issued a press release relating to the material change.  The press release was disseminated via Canada NewsWire.

Item 4. Summary of Material Change

On May 23, 2006, Dr. Mike Abrams stepped down as President and Chief Executive Officer of the Company.  Dr. Abrams also resigned as a director of the Company.

Item 5. Full Description of Material Change

On May 23, 2006, Dr. Mike Abrams stepped down as President and Chief Executive Officer of the Company.  Dr. Abrams also resigned as a director of the Company.  Kenneth Galbraith, Chairman of the Company, will serve as Interim Chief Executive Officer of the Company and Paul Brennan, Vice President, Business Development of the Company, will serve as Acting President of the Company.

Item 6. Reliance on subsection 7.1(2) or (3) of National Instrument 51-102

Not applicable.

Item 7. Omitted Information

No significant facts remain confidential and no information has been omitted in this report.

Item 8. Executive Officer

Name of Executive Officer:

W.J. (Bill) Adams

Chief Financial Officer, Vice President, Finance,
Secretary and Treasurer

Telephone Number:

604-530-1057

Item 9. Date of Report

May 26, 2006